Clinicopathologic Characteristics of Ovarian Carcinoma in Hasan Sadikin General Hospital Bandung

Abstract

Background:

Ovarian carcinoma (OC) has several subtypes with overlapping histopathological presentation and usually has a poor prognosis. According to WHO, ovarian Mucinous Carcinoma (MC) is the most common subtype of OC in Southeast Asia, especially Indonesia.

Objectives:

This study aimed to report the incidence and clinicopathologic characteristics of OC between 2018-2023 tertiary Hospital in Bandung, Indonesia

Materials and Methods:

We conducted a descriptive study, collecting OC data from medical records in Hasan Sadikin General Hospital, a tertiary referral hospital.

Results:

The most common subtypes from 460 patients were MC (n=460;32%) based on histomorphology and immunohistochemistry, followed by Ovarian Endometrioid Carcinoma (EC) (n=460;21%). The mean age was 47.89 years (range 14-81). We revealed EC's incidence was higher than ovarian High-Grade Serous Carcinoma (HGSC) (21% vs. 18%), discordant with the WHO report as the most common subtype. The largest OC reported was 70 cm in the greatest dimension found in MC, and the smallest OC was 3 cm found in Ovarian Clear Cell Carcinoma.

Conclusion:   

The most common subtype of ovarian carcinoma was ovarian mucinous carcinoma; the overall mean age was 47.89 years. The largest ovarian carcinoma was mucinous carcinoma, with 70 cm in the greatest dimension.