Clinicopathologic Characteristics of Ovarian Carcinoma in Hasan Sadikin General Hospital Bandung

Abstract

Background

Ovarian carcinoma (OC) has several subtypes with overlapping histopathological presentation and usually has a poor prognosis. According to WHO, ovarian Mucinous Carcinoma (MC) is the most common subtype of OC in Southeast Asia, especially Indonesia.

Objectives

This study aimed to report the incidence and clinicopathologic characteristics of OC between 2018-2023 tertiary Hospital in Bandung, Indonesia

Materials and Methods

We conducted a descriptive study, collecting OC data from medical records in Hasan Sadikin General Hospital, a tertiary referral hospital.

Results:

The most common subtypes from 460 patients were MC (n=460;32%) based on histomorphology and immunohistochemistry, followed by Ovarian Endometrioid Carcinoma (EC) (n=460;21%). The mean age was 47.89 years (range 14-81). We revealed EC's incidence was higher than ovarian High-Grade Serous Carcinoma (HGSC) (21% vs. 18%), discordant with the WHO report as the most common subtype. The largest OC reported was 70 cm in the greatest dimension found in MC, and the smallest OC was 3 cm found in Ovarian Clear Cell Carcinoma.

Conclusion

The most common subtype of ovarian carcinoma was ovarian mucinous carcinoma; the overall mean age was 47.89 years. The largest ovarian carcinoma was mucinous carcinoma, with 70 cm in the greatest dimension.